منابع مشابه
Sufentanil transfer in the human placenta during in vitro perfusion.
PURPOSE Sufentanil, a lipophilic opioid, is used to provide analgesia for labour and Caesarean section, but may cause neonatal depression. Factors affecting placental transfer of sufentanil were investigated using human placentas. STUDY DESIGN Transfer and uptake of sufentanil by the human placenta were studied using a single pass (open) in vitro perfusion model. The effects of change in sufe...
متن کاملTransfer of dideoxyinosine across the human isolated placenta.
1. Dideoxyinosine (ddI) has recently been approved for the treatment of patients with HIV infection. As increasing numbers of such patients are pregnant, we wished to define the rate and mechanism(s) of ddI transfer by the placenta to the foetus. Using isolated single perfused human term placental cotyledons, the drug was shown to cross the placenta from mother to foetus at a rate of 25% that o...
متن کاملIsolated lung perfusion.
Isolated lung perfusion (ILP) has been historically used as a method to study basic lung physiologic concepts using animal models. More recently, ILP has been applied in lung transplantation and thoracic oncology. In lung transplantation, ILP has been used to assess physiological integrity of donor lungs after the organ is removed from the donor. This procedure is called Ex vivo Lung Perfusion ...
متن کاملTransfer of meropenem in the ex vivo human placenta perfusion model.
OBJECTIVES To determine maternal-fetal transplacental passage of meropenem in the ex vivo human perfusion model. STUDY DESIGN Term placentae (n = 6) were collected immediately after delivery. A single cotyledon was localized, perfused and stabilized with physiologic Eagles minimal essential medium containing 3% bovine albumin and heparin as described by Chalier (Chalier JC. Criteria for evalu...
متن کاملPerfusion of isolated renal tubules.
The metlhodls usedl for perftusinig isolatedi renal tul)ules are generally clifferent from microptuncture, as are the prob)lems encounteredl. Altlhotuglh I will concentrate maiinly on the teclhnical aslpects of perfuision, it seems to me most important to evaluate to wlhat extent the restults are p)ertinent to the stt(ly of kidney function. Are the tubules still "alive?' Are they still fuinctio...
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ژورنال
عنوان ژورنال: Proceedings of the Nutrition Society
سال: 1991
ISSN: 0029-6651,1475-2719
DOI: 10.1079/pns19910044